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I'm left handed (yay!) but I think it's a suggestion that can also be usefull for right handed.
I usually prefer to use the little two arrows icon to slide incrementally my values in my menus (brushs or guideline panels for exemple), but if the menu is on the right of my screen or if I have to slide too far left, I can't find my value cause there is the border of the screen... And it's a pain to slide multiple times so I end up using my keyboard (small bluetooth keyboard with no num pad haha)
So the idea is : could it be possible either to choose beetween sliding vertically or horizontally, like for flipping? Or maybe both : up and right to increment, down and left to decrement? Would solve a lot of UI disconfort for me.